TH-Z816 is an inhibitor of KRAS(G12D) with an IC50 of 14 μM in an SOS-catalyzed nucleotide exchange assay with GDP as the incoming nucleotide.
MedKoo Cat#: 127372
Name: TH-Z816
CAS#: 2847881-42-7
Chemical Formula: C29H38N6O
Exact Mass: 486.3107
Molecular Weight: 486.66
Elemental Analysis: C, 71.57; H, 7.87; N, 17.27; O, 3.29
The following data is based on the product molecular weight 486.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
