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MedKoo Cat#: 150061 | Name: Ethyl maltol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ethyl maltol, a key food additive, and flavor enhancer is safe and is the most common sweet-associated component in electronic cigarette liquids.

Chemical Structure

Ethyl maltol
Ethyl maltol
CAS#4940-11-8

Theoretical Analysis

MedKoo Cat#: 150061

Name: Ethyl maltol

CAS#: 4940-11-8

Chemical Formula: C7H8O3

Exact Mass: 140.0470

Molecular Weight: 140.14

Elemental Analysis: C, 60.00; H, 5.75; O, 34.25

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ethyl maltol;
IUPAC/Chemical Name
2-Ethyl-3-hydroxy-4H-pyran-4-one
InChi Key
YIKYNHJUKRTCJL-UHFFFAOYSA-N
InChi Code
1S/C7H8O3/c1-2-6-7(9)5(8)3-4-10-6/h3-4,9H,2H2,1H3
SMILES Code
O=C1C(O)=C(CC)OC=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 140.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sun Y, Bressler J. Ethyl maltol disrupt iron homeostasis in SH-SY5Y neuroblastoma cell line. J Biochem Mol Toxicol. 2023 Dec;37(12):e23504. doi: 10.1002/jbt.23504. Epub 2023 Aug 22. PMID: 37606557. 2: Durrani K, El Din SA, Sun Y, Rule AM, Bressler J. Ethyl maltol enhances copper mediated cytotoxicity in lung epithelial cells. Toxicol Appl Pharmacol. 2021 Jan 1;410:115354. doi: 10.1016/j.taap.2020.115354. Epub 2020 Nov 30. PMID: 33271249. 3: Omaiye EE, Luo W, McWhirter KJ, Pankow JF, Talbot P. Ethyl maltol, vanillin, corylone and other conventional confectionery-related flavour chemicals dominate in some e-cigarette liquids labelled 'tobacco' flavoured. Tob Control. 2022 Nov;31(Suppl 3):s238-s244. doi: 10.1136/tc-2022-057484. PMID: 36328460; PMCID: PMC9664106. 4: Xing P, Che Z, Liu Y, He J, Wei R, Chen L, Zhang S, Huang X, Yang Y, Liu S, Chen G, Tian Y. Synthesis and Anti-Oomycete Preliminary Mechanism of Sulfonate Derivatives of Ethyl Maltol. Chem Biodivers. 2022 Jun;19(6):e202200255. doi: 10.1002/cbdv.202200255. Epub 2022 May 27. PMID: 35560978. 5: Li Z, Lu J, Wu C, Pang Q, Zhu Z, Nan R, Du R, Chen J. Toxicity Studies of Ethyl Maltol and Iron Complexes in Mice. Biomed Res Int. 2017;2017:2640619. doi: 10.1155/2017/2640619. Epub 2017 Jan 19. PMID: 28197411; PMCID: PMC5288557. 6: Sahu G, Patra SA, Pattanayak PD, Kaminsky W, Dinda R. LVVO-Ethyl Maltol-Based Metallodrugs (L2- = Tridentate ONO Ligands): Hydrophobicity, Hydrolytic Stability, and Cytotoxicity via ROS-Mediated Apoptosis. Inorg Chem. 2023 May 1;62(17):6722-6739. doi: 10.1021/acs.inorgchem.3c00326. Epub 2023 Apr 19. PMID: 37074879.