MMV1088447 | Parasite Growth Inhibitor

MedKoo Cat#: 150057 | Name: MMV1088447

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MMV1088447 is a novel parasite growth inhibitor. MMV1088447 exhibits profiles similar to cells treated with nuclear hormone receptor (NHR) agonist/antagonists. MMV1088447 significantly impairs parasite growth by downregulation of host lipid metabolism.

Chemical Structure

MMV1088447

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 150057

Name: MMV1088447

CAS#: N/A

Chemical Formula: C19H18N2O4

Exact Mass: 338.1270

Molecular Weight: 338.36

Elemental Analysis: C, 67.45; H, 5.36; N, 8.28; O, 18.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

MMV1088447; MMV 1088447; MMV-1088447;

IUPAC/Chemical Name

2-Carbamoylphenyl 1-(furan-2-ylmethyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate

InChi Key

ONABHHAASBYICU-UHFFFAOYSA-N

InChi Code

1S/C19H18N2O4/c1-12-10-16(13(2)21(12)11-14-6-5-9-24-14)19(23)25-17-8-4-3-7-15(17)18(20)22/h3-10H,11H2,1-2H3,(H2,20,22)

SMILES Code

O=C(C1=C(C)N(CC2=CC=CO2)C(C)=C1)OC3=CC=CC=C3C(N)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 338.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Mittal N, Davis C, McLean P, Calla J, Godinez-Macias KP, Gardner A, Healey D, Orjuela-Sanchez P, Ottilie S, Chong Y, Gibson C, Winzeler EA. Human nuclear hormone receptor activity contributes to malaria parasite liver stage development. Cell Chem Biol. 2023 May 18;30(5):486-498.e7. doi: 10.1016/j.chembiol.2023.04.011. Epub 2023 May 11. PMID: 37172592; PMCID: PMC10878326.