KF-19418 | CAS#147508-06-3 | hair growth promoter

MedKoo Cat#: 145234 | Name: KF-19418

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KF-19418 stimulates proliferation of cultured hair bulb cells from new born mice in concentration-dependent manner in the range under 10 microM. KF19418 promoted hair follicle elongation as in the case of minoxidil. KF19418 directly stimulated hair follicle in vitro and has hair growth promoting activities in vivo.

Chemical Structure

KF-19418

CAS#147508-06-3

Theoretical Analysis

MedKoo Cat#: 145234

Name: KF-19418

CAS#: 147508-06-3

Chemical Formula: C21H14N4O

Exact Mass: 338.1168

Molecular Weight: 338.37

Elemental Analysis: C, 74.54; H, 4.17; N, 16.56; O, 4.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

KF-19418; KF19418;

IUPAC/Chemical Name

3,5-diphenyl-1,5-dihydro-4H-pyrazolo[4,3-c][1,8]naphthyridin-4-one

InChi Key

UUTQKSICTCJBNB-UHFFFAOYSA-N

InChi Code

1S/C21H14N4O/c26-21-17-18(14-8-3-1-4-9-14)23-24-19(17)16-12-7-13-22-20(16)25(21)15-10-5-2-6-11-15/h1-13H,(H,23,24)

SMILES Code

O=C1N(C2=CC=CC=C2)C3=NC=CC=C3C4=C1C(=NN4)C5=CC=CC=C5

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 338.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Shirai A, Ikeda J, Kawashima S, Tamaoki T, Kamiya T. KF19418, a new compound for hair growth promotion in vitro and in vivo mouse models. J Dermatol Sci. 2001 Apr;25(3):213-8. doi: 10.1016/s0923-1811(00)00147-x. PMID: 11240269.