MedKoo Cat#: 150037 | Name: CIAC001

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CIAC001 is a cannabidiol derivative. CIA001 exhibits significantly improved anti-neuroinflammatory activity with lower toxicity in vitro. CIA001 ameliorates the morphine-induced withdrawal reaction, behavioral sensitization, and conditional position in vivo.

Chemical Structure

CIAC001
CIAC001
CAS#2649154-82-3

Theoretical Analysis

MedKoo Cat#: 150037

Name: CIAC001

CAS#: 2649154-82-3

Chemical Formula: C20H25N3O2

Exact Mass: 339.1950

Molecular Weight: 339.44

Elemental Analysis: C, 70.77; H, 7.42; N, 12.38; O, 9.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CIAC001; CIAC-001; CIAC 001;
IUPAC/Chemical Name
(1'R,2'R)-4-(1-(2H-1,2,3-Triazol-2-yl)ethyl)-5'-methyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2,6-diol
InChi Key
AGJUGOFAIPQXTD-MWSTZMHHSA-N
InChi Code
1S/C20H25N3O2/c1-12(2)16-6-5-13(3)9-17(16)20-18(24)10-15(11-19(20)25)14(4)23-21-7-8-22-23/h7-11,14,16-17,24-25H,1,5-6H2,2-4H3/t14?,16-,17+/m0/s1
SMILES Code
OC1=CC(C(N2N=CC=N2)C)=CC(O)=C1[C@H]3[C@H](C(C)=C)CCC(C)=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 339.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jin S, Lin C, Wang Y, Wang H, Wen X, Xiao P, Li X, Peng Y, Sun J, Lu Y, Wang X. Cannabidiol Analogue CIAC001 for the Treatment of Morphine-Induced Addiction by Targeting PKM2. J Med Chem. 2023 Aug 24;66(16):11498-11516. doi: 10.1021/acs.jmedchem.3c01029. Epub 2023 Aug 2. PMID: 37531582.