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MedKoo Cat#: 150036 | Name: LUF7960

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LUF7960 is a covalent electrophilic hA3AR antagonist.

Chemical Structure

LUF7960
LUF7960
CAS#2941609-83-0

Theoretical Analysis

MedKoo Cat#: 150036

Name: LUF7960

CAS#: 2941609-83-0

Chemical Formula: C26H26FN5O6S

Exact Mass: 555.1590

Molecular Weight: 555.58

Elemental Analysis: C, 56.21; H, 4.72; F, 3.42; N, 12.61; O, 17.28; S, 5.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LUF7960; LUF 7960; LUF-7960;
IUPAC/Chemical Name
4-((4-(2,4-Dioxo-8-(prop-2-yn-1-yloxy)-3-propyl-3,4-dihydropyrido[2,1-f]purin-1(2H)-yl)butyl)carbamoyl)benzenesulfonyl fluoride
InChi Key
XCDNNNMEBBOOQS-UHFFFAOYSA-N
InChi Code
1S/C26H26FN5O6S/c1-3-13-32-25(34)22-23(29-21-17-19(38-16-4-2)11-15-30(21)22)31(26(32)35)14-6-5-12-28-24(33)18-7-9-20(10-8-18)39(27,36)37/h2,7-11,15,17H,3,5-6,12-14,16H2,1H3,(H,28,33)
SMILES Code
O=S(C1=CC=C(C(NCCCCN(C(N2CCC)=O)C3=C(N4C(C=C(OCC#C)C=C4)=N3)C2=O)=O)C=C1)(F)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 555.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Beerkens BLH, Snijders IM, Snoeck J, Liu R, Tool ATJ, Le Dévédec SE, Jespers W, Kuijpers TW, van Westen GJP, Heitman LH, IJzerman AP, van der Es D. Development of an Affinity-Based Probe to Profile Endogenous Human Adenosine A3 Receptor Expression. J Med Chem. 2023 Aug 24;66(16):11399-11413. doi: 10.1021/acs.jmedchem.3c00854. Epub 2023 Aug 2. PMID: 37531576; PMCID: PMC10461224.