RNF5 inhibitor FX12, also known as FX12, is a inhibitor and degrader of RNF5. FX12 acts as a selective small-molecule inhibitor and degrader of RNF5. FX12 binds to RNF5 and inhibits its E3 activity in vitro as well as promoting proteasomal degradation of RNF5 in cells. RNF5 as a molecular target for FX12 was supported by the facts that FX12 requires RNF5 to inhibit dislocation and negatively regulates RNF5 function.
MedKoo Cat#: 150024
Name: RNF5 inhibitor FX12
CAS#: 1807639-36-6
Chemical Formula: C10H8O4S
Exact Mass: 224.0143
Molecular Weight: 224.23
Elemental Analysis: C, 53.57; H, 3.60; O, 28.54; S, 14.30
The following data is based on the product molecular weight 224.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
