GSK1820795A | G2A | GPR132 | antagonist | CAS#2650253-86-2

MedKoo Cat#: 127308 | Name: GSK1820795A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GSK1820795A is a Potent and Selective G2A (GPR132) antagonist.

Chemical Structure

GSK1820795A

CAS#2650253-86-2

Theoretical Analysis

MedKoo Cat#: 127308

Name: GSK1820795A

CAS#: 2650253-86-2

Chemical Formula: C35H34N8

Exact Mass: 566.2906

Molecular Weight: 566.71

Elemental Analysis: C, 74.18; H, 6.05; N, 19.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

GSK-1820795A; GSK 1820795A; GSK1820795A

IUPAC/Chemical Name

5-(1-butylbenzimidazol-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]indazole

InChi Key

XRXMDDDFTLKJHL-UHFFFAOYSA-N

InChi Code

InChI=1S/C35H34N8/c1-3-5-21-42-32-13-9-8-12-31(32)36-35(42)26-18-19-30-29(23-26)33(43(39-30)20-4-2)22-24-14-16-25(17-15-24)27-10-6-7-11-28(27)34-37-40-41-38-34/h6-19,23H,3-5,20-22H2,1-2H3,(H,37,38,40,41)

SMILES Code

CCCN1N=C2C=CC(C3=NC4=CC=CC=C4N3CCCC)=CC2=C1CC5=CC=C(C6=CC=CC=C6C7=NNN=N7)C=C5

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 566.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Foster JR, Ueno S, Chen MX, Harvey J, Dowell SJ, Irving AJ, Brown AJ. N-Palmitoylglycine and other N-acylamides activate the lipid receptor G2A/GPR132. Pharmacol Res Perspect. 2019 Nov 21;7(6):e00542. doi: 10.1002/prp2.542. PMID: 31768260; PMCID: PMC6868653.