Synonym
Pteleine; Ptelein;
IUPAC/Chemical Name
4,6-dimethoxyfuro[2,3-b]quinoline
InChi Key
ALLQMEDAYDKMIO-UHFFFAOYSA-N
InChi Code
1S/C13H11NO3/c1-15-8-3-4-11-10(7-8)12(16-2)9-5-6-17-13(9)14-11/h3-7H,1-2H3
SMILES Code
COC1=CC2=C(OC)C3=C(OC=C3)N=C2C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
229.24
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: El Sayed K, Al-Said MS, El-Feraly FS, Ross SA. New quinoline alkaloids from Ruta chalepensis. J Nat Prod. 2000 Jul;63(7):995-7. doi: 10.1021/np000012y. PMID: 10924184.
2: Paulini H, Eilert U, Schimmer O. Mutagenic compounds in an extract from rutae herba (Ruta graveolens L.). I. Mutagenicity is partially caused by furoquinoline alkaloids. Mutagenesis. 1987 Jul;2(4):271-3. doi: 10.1093/mutage/2.4.271. PMID: 3325757.
3: Kuwayama Y, Ota T, Mikata T, Kanda H. [Studies on making use of gamma- butyrolactone. XIV. Synthesis of furoquinoline alkaloid "pteleine"]. Yakugaku Zasshi. 1968 Aug;88(8):1050-3. Japanese. doi: 10.1248/yakushi1947.88.8_1050. PMID: 5751460.
4: Yang X, Feng Y, Duffy S, Avery VM, Camp D, Quinn RJ, Davis RA. A new quinoline epoxide from the Australian plant Drummondita calida. Planta Med. 2011 Sep;77(14):1644-7. doi: 10.1055/s-0030-1270963. Epub 2011 Apr 6. PMID: 21472648.
5: Mitscher LA, Bathala MS, Clark GW, Beal JL. Antimicrobial agents from higher plants. The antimicrobially inactive components of Ptelea trifoliata L. Lloydia. 1975 Mar-Apr;38(2):117-24. PMID: 1134209.
6: Pusset J, Lopez JL, Pais M, Neirabeyeh MA, Veillon JM. Isolation and 2D NMR Studies of Alkaloids from Comptonella sessilifoliola1. Planta Med. 1991 Apr;57(2):153-5. doi: 10.1055/s-2006-960053. PMID: 17226139.
7: Liu Y, Chen J, Li XH, Shi YP. Simultaneous determination of seven alkaloids in Phellodendron chinense Schneid by high-performance liquid chromatography. J AOAC Int. 2010 Sep-Oct;93(5):1416-21. PMID: 21140651.
