Synonym
Sonoflora 1; Sonoflora1; Sonoflora-1; SF1; SF-1; SF 1.
IUPAC/Chemical Name
Stannate(3-), [N-[2-[(7S,8S)-3-carboxy-7-(2-carboxyethyl)-13-ethenyl-18-ethyl-2,8,12,17-tetramethyl-21H,23H-porphin-5-yl-κN21,κN22,κN23,κN24]acetyl]glycylglycinato(5-)]dihydroxy-, sodium (1:3), (OC-6-13)-
InChi Key
YFKGEMWMQNGXOZ-IGVQWUNUSA-G
InChi Code
InChI=1S/C38H42N6O8.3Na.2H2O.Sn/c1-7-21-17(3)25-12-27-19(5)23(9-10-33(47)48)36(43-27)24(11-31(45)39-15-32(46)40-16-34(49)50)37-35(38(51)52)20(6)28(44-37)14-30-22(8-2)18(4)26(42-30)13-29(21)41-25;;;;;;/h7,12-14,19,23H,1,8-11,15-16H2,2-6H3,(H7,39,40,41,42,43,44,45,46,47,48,49,50,51,52);;;;2*1H2;/q;3*+1;;;+4/p-7/t19-,23-;;;;;;/m0....../s1
SMILES Code
O=C(NCC(NCC(O[Na])=O)=O)C/C1=C2[C@@H](CCC(O[Na])=O)[C@H](C)C(/C=C3C(C)=C(C=C)/C4=C/C(C(C)=C/5CC)=NC5=C/C6=C(C)C(C(O[Na])=O)=C1N6[Sn-2]([OH+])([OH+])N4/3)=N\2
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Sonodynamic therapy (SDT) has been developed as a complementary or alternative therapy to PDT. There are data to show that an additive effect might be obtained if SDT is combined with PDT. There are also data showing that PDT is synergistic with chemotherapeutic agents. In SDT treatment, patients first ingest a sonosensitizer, a drug that can be activated by ultrasound. This drug is then activated through the use of low-intensity ultrasound, producing a cascade of endogenous cytotoxic agents. The therapy is thus similar to PDT, except that the sensitizer is activated by ultrasound rather than by light. The body transmits ultrasound much more efficiently than light, and this is a decisive advantage when treating deeper tumors. ( Source: Integr Cancer Ther 8(3) (2009) 283)
