IUPAC/Chemical Name
3-(4-chloro-2,6-dimethylphenyl)-8-methoxy-1-methyl-2-oxo-1,8-diazaspiro[4.5]dec-3-en-4-yl ethyl carbonate
InChi Key
WOPFPAIGRGHWAQ-UHFFFAOYSA-N
InChi Code
1S/C21H27ClN2O5/c1-6-28-20(26)29-18-17(16-13(2)11-15(22)12-14(16)3)19(25)23(4)21(18)7-9-24(27-5)10-8-21/h11-12H,6-10H2,1-5H3
SMILES Code
CCOC(=O)OC1=C(C(=O)N(C)C12CCN(CC2)OC)C3=C(C)C=C(Cl)C=C3C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
422.91
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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3: EFSA (European Food Safety Authority). Assessment of fall-back MRLs for revoked CXLs previously implemented in the EU legislation and review of the JMPR evaluation of the toxicological data related to pyrasulfotole, pyraziflumid, spiropidion and tetraniliprole. EFSA J. 2024 May 21;22(5):e8693. doi: 10.2903/j.efsa.2024.8693. PMID: 38774114; PMCID: PMC11106678.
4: Wu Z, Ma Y, Xiong H, An W, Zhang Y, Zhao Q, Li J. Simultaneous determination of spiropidion and its five major metabolites in sweet orange fruit and various processing by-products using ultra-high performance liquid chromatography-tandem mass spectrometry. Food Res Int. 2023 Dec;174(Pt 1):113498. doi: 10.1016/j.foodres.2023.113498. Epub 2023 Sep 29. PMID: 37986498.
5: Muehlebach M, Buchholz A, Zambach W, Schaetzer J, Daniels M, Hueter O, Kloer DP, Lind R, Maienfisch P, Pierce A, Pitterna T, Smejkal T, Stafford D, Wildsmith L. Spiro N-methoxy piperidine ring containing aryldiones for the control of sucking insects and mites: discovery of spiropidion. Pest Manag Sci. 2020 Oct;76(10):3440-3450. doi: 10.1002/ps.5743. Epub 2020 Feb 6. PMID: 31943711.
