MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 127250 | Name: VU10004

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VU10004 is a M4 PAM (IC50 = 106 nM).

Chemical Structure

VU10004
VU10004
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 127250

Name: VU10004

CAS#: N/A

Chemical Formula: C13H15N3OS

Exact Mass: 261.0936

Molecular Weight: 261.34

Elemental Analysis: C, 59.75; H, 5.79; N, 16.08; O, 6.12; S, 12.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
VU10004; VU-10004; VU 10004
IUPAC/Chemical Name
3-amino-N-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
InChi Key
UUPIXVFXQKCVSJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H15N3OS/c1-6-5-7(2)15-13-9(6)10(14)11(18-13)12(17)16-8-3-4-8/h5,8H,3-4,14H2,1-2H3,(H,16,17)
SMILES Code
CC1=CC(C)=C2C(SC(C(NC3CC3)=O)=C2N)=N1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 261.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Huynh T, Valant C, Crosby IT, Sexton PM, Christopoulos A, Capuano B. Synthesis and pharmacological evaluation of M4 muscarinic receptor positive allosteric modulators derived from VU10004. ACS Chem Neurosci. 2015 Jun 17;6(6):838-44. doi: 10.1021/acschemneuro.5b00035. Epub 2015 Apr 17. PMID: 25857219.