MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 145133 | Name: Dibutylone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dibutylone is a new psychoactive substance of the cathinone class. Dibutylone demonstrates significant stimulant effects and fully substitutes for the discriminative stimulus effects of methamphetamine, cocaine, and MDMA , indicating its potential for abuse as a psychoactive substance similar to other tested compounds.

Chemical Structure

Dibutylone
Dibutylone
CAS#802286-83-5

Theoretical Analysis

MedKoo Cat#: 145133

Name: Dibutylone

CAS#: 802286-83-5

Chemical Formula: C13H17NO3

Exact Mass: 235.1208

Molecular Weight: 235.28

Elemental Analysis: C, 66.36; H, 7.28; N, 5.95; O, 20.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Dibutylone; BK-DMBDB; bk-MMBDB
IUPAC/Chemical Name
1-(benzo[d][1,3]dioxol-5-yl)-2-(dimethylamino)butan-1-one
InChi Key
USEBIPUIVPERGC-UHFFFAOYSA-N
InChi Code
1S/C13H17NO3/c1-4-10(14(2)3)13(15)9-5-6-11-12(7-9)17-8-16-11/h5-7,10H,4,8H2,1-3H3
SMILES Code
CCC(N(C)C)C(=O)C1=CC=C2OCOC2=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 235.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Krotulski AJ, Mohr ALA, Papsun DM, Logan BK. Dibutylone (bk-DMBDB): Intoxications, Quantitative Confirmations and Metabolism in Authentic Biological Specimens. J Anal Toxicol. 2018 Sep 1;42(7):437-445. doi: 10.1093/jat/bky022. PMID: 29554274. 2: Lai M, Fu D, Xu Z, Du H, Liu H, Wang Y, Xu P, Zhou W. Relative reinforcing effects of dibutylone, ethylone, and N-ethylpentylone: self-administration and behavioral economics analysis in rats. Psychopharmacology (Berl). 2022 Sep;239(9):2875-2884. doi: 10.1007/s00213-022-06173-x. Epub 2022 Jun 18. PMID: 35716192. 3: Wang KD, Cao FQ, Jiang X, Chen H, Yuan XL, Chen YS, Hu JJ. Identification of the New Psychoactive Substance Dibutylone. Fa Yi Xue Za Zhi. 2019 Dec;35(6):682-686. English, Chinese. doi: 10.12116/j.issn.1004-5619.2019.06.007. Epub 2019 Dec 25. PMID: 31970954. 4: Gatch MB, Dolan SB, Forster MJ. Locomotor activity and discriminative stimulus effects of five novel synthetic cathinone analogs in mice and rats. Drug Alcohol Depend. 2019 Jun 1;199:50-58. doi: 10.1016/j.drugalcdep.2019.02.016. Epub 2019 Apr 6. PMID: 30986635; PMCID: PMC6534427. 5: Adamowicz P, Malczyk A. Stability of synthetic cathinones in blood and urine. Forensic Sci Int. 2019 Feb;295:36-45. doi: 10.1016/j.forsciint.2018.12.001. Epub 2018 Dec 6. PMID: 30557825. 6: Glatfelter GC, Walther D, Evans-Brown M, Baumann MH. Eutylone and Its Structural Isomers Interact with Monoamine Transporters and Induce Locomotor Stimulation. ACS Chem Neurosci. 2021 Apr 7;12(7):1170-1177. doi: 10.1021/acschemneuro.0c00797. Epub 2021 Mar 9. PMID: 33689284; PMCID: PMC9423000. 7: Lau T, Concheiro M, Cooper G. Determination of 30 Synthetic Cathinones in Postmortem Blood Using LC-MS-MS. J Anal Toxicol. 2020 Oct 12;44(7):679-687. doi: 10.1093/jat/bkaa071. PMID: 32591789. 8: Gampfer TM, Wagmann L, Pulver B, Westphal F, Flockerzi V, Meyer MR. A simplified strategy to assess the cytotoxicity of new psychoactive substances in HepG2 cells using a high content screening assay - Exemplified for nine compounds. Toxicology. 2022 Jun 30;476:153258. doi: 10.1016/j.tox.2022.153258. Epub 2022 Jul 13. PMID: 35842060. 9: Bade R, Eaglesham G, Shimko KM, Mueller J. Quantification of new psychoactive substances in Australian wastewater utilising direct injection liquid chromatography coupled to tandem mass spectrometry. Talanta. 2023 Jan 1;251:123767. doi: 10.1016/j.talanta.2022.123767. Epub 2022 Aug 8. PMID: 35973252. 10: Shirley Lee HZ, Koh HB, Tan S, Goh BJ, Lim R, Lim JLW, Angeline Yap TW. Identification of closely related new psychoactive substances (NPS) using solid deposition gas-chromatography infra-red detection (GC-IRD) spectroscopy. Forensic Sci Int. 2019 Jun;299:21-33. doi: 10.1016/j.forsciint.2019.03.025. Epub 2019 Mar 23. PMID: 30954004. 11: Giachetti AD, Kahl JH, Zaney ME, Hime GW, Boland DM. Method Validation of Seven Synthetic Cathinones by LC-MS/MS Analysis and the Prevalence of N-Ethylpentylone in Postmortem Casework. J Anal Toxicol. 2020 Dec 11:bkaa194. doi: 10.1093/jat/bkaa194. Epub ahead of print. PMID: 33305793. 12: Mohr ALA, Fogarty MF, Krotulski AJ, Logan BK. Evaluating Trends in Novel Psychoactive Substances Using a Sentinel Population of Electronic Dance Music Festival Attendees. J Anal Toxicol. 2021 May 14;45(5):490-497. doi: 10.1093/jat/bkaa104. PMID: 32860703. 13: Ameline A, Garnier D, Gheddar L, Richeval C, Gaulier JM, Raul JS, Kintz P. Identification and analytical characterization of seven NPS, by combination of 1H NMR spectroscopy, GC-MS and UPLC-MS/MS®, to resolve a complex toxicological fatal case. Forensic Sci Int. 2019 May;298:140-148. doi: 10.1016/j.forsciint.2019.03.003. Epub 2019 Mar 9. PMID: 30903949. 14: Krotulski AJ, Mohr ALA, Fogarty MF, Logan BK. The Detection of Novel Stimulants in Oral Fluid from Users Reporting Ecstasy, Molly and MDMA Ingestion. J Anal Toxicol. 2018 Oct 1;42(8):544-553. doi: 10.1093/jat/bky051. PMID: 30371847.