MedKoo Cat#: 145130 | Name: Tiadinil

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tiadinil is a plant activator that acts by inducing defense mechanisms against pathogenic fungi on tea leaves. Tiadinil enhances the production of herbivore-induced plant volatiles that attract predatory mites, such as Neoseiulus womersleyi, which are natural enemies of the herbivorous mite Tetranychus kanzawai.

Chemical Structure

Tiadinil
Tiadinil
CAS#223580-51-6

Theoretical Analysis

MedKoo Cat#: 145130

Name: Tiadinil

CAS#: 223580-51-6

Chemical Formula: C11H10ClN3OS

Exact Mass: 267.0233

Molecular Weight: 267.73

Elemental Analysis: C, 49.35; H, 3.76; Cl, 13.24; N, 15.70; O, 5.98; S, 11.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Tiadinil; Saixianjunan; V-GET;
IUPAC/Chemical Name
N-(3-chloro-4-methylphenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide
InChi Key
VJQYLJSMBWXGDV-UHFFFAOYSA-N
InChi Code
1S/C11H10ClN3OS/c1-6-3-4-8(5-9(6)12)13-11(16)10-7(2)14-15-17-10/h3-5H,1-2H3,(H,13,16)
SMILES Code
CC1=C(SN=N1)C(=O)NC2=CC(Cl)=C(C)C=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 267.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Maeda T, Ishiwari H. Tiadinil, a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles that attract the predatory mite Neoseiulus womersleyi in the tea plant Camellia sinensis. Exp Appl Acarol. 2012 Nov;58(3):247-58. doi: 10.1007/s10493-012-9577-2. Epub 2012 Jun 6. PMID: 22669277. 2: Chen X, Zhao K, Fan Z, Mao W, Li J, Ji X, Hua X, Zong G, Li F. Determination of tiadinil and its metabolite in flue-cured tobacco. J Chromatogr Sci. 2014 Aug;52(7):624-8. doi: 10.1093/chromsci/bmt090. Epub 2013 Jul 3. PMID: 23825350. 3: Kalinina TA, Balandina VI, Obydennov KL, Slepukhin PA, Fan Z, Bakulev VA, Glukhareva TV. Synthesis, Fungicidal Activity and Plant Protective Properties of 1,2,3-Thiadiazole and Isothiazole-Based N-acyl-N-arylalaninates. Molecules. 2023 Jan 3;28(1):419. doi: 10.3390/molecules28010419. PMID: 36615609; PMCID: PMC9822468. 4: Shimono M, Koga H, Akagi A, Hayashi N, Goto S, Sawada M, Kurihara T, Matsushita A, Sugano S, Jiang CJ, Kaku H, Inoue H, Takatsuji H. Rice WRKY45 plays important roles in fungal and bacterial disease resistance. Mol Plant Pathol. 2012 Jan;13(1):83-94. doi: 10.1111/j.1364-3703.2011.00732.x. Epub 2011 Jul 4. PMID: 21726399; PMCID: PMC6638719. 5: Kimura N, Fukuchi A. MBI-D resistance management of Pyricularia oryzae using an application program incorporating benomyl. J Pestic Sci. 2018 Feb 28;43(1):33-35. doi: 10.1584/jpestics.D17-064. PMID: 30363090; PMCID: PMC6140615. 6: Fan Z, Shi Z, Zhang H, Liu X, Bao L, Ma L, Zuo X, Zheng Q, Mi N. Synthesis and biological activity evaluation of 1,2,3-thiadiazole derivatives as potential elicitors with highly systemic acquired resistance. J Agric Food Chem. 2009 May 27;57(10):4279-86. doi: 10.1021/jf8031364. Epub 2009 Apr 15. PMID: 21314199. 7: Pye MF, Hakuno F, Macdonald JD, Bostock RM. Induced resistance in tomato by SAR activators during predisposing salinity stress. Front Plant Sci. 2013 May 6;4:116. doi: 10.3389/fpls.2013.00116. PMID: 23653630; PMCID: PMC3644939.