MedKoo Cat#: 145125 | Name: Ipflufenoquin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ipflufenoquin, an agrochemical fungicide, shares its mode-of-action with a new antifungal olorofim.

Chemical Structure

Ipflufenoquin
Ipflufenoquin
CAS#1314008-27-9

Theoretical Analysis

MedKoo Cat#: 145125

Name: Ipflufenoquin

CAS#: 1314008-27-9

Chemical Formula: C19H16F3NO2

Exact Mass: 347.1133

Molecular Weight: 347.34

Elemental Analysis: C, 65.70; H, 4.64; F, 16.41; N, 4.03; O, 9.21

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ipflufenoquin;
IUPAC/Chemical Name
2-(2-((7,8-difluoro-2-methylquinolin-3-yl)oxy)-6-fluorophenyl)propan-2-ol
InChi Key
DSXOWZNZGWXWMX-UHFFFAOYSA-N
InChi Code
1S/C19H16F3NO2/c1-10-15(9-11-7-8-13(21)17(22)18(11)23-10)25-14-6-4-5-12(20)16(14)19(2,3)24/h4-9,24H,1-3H3
SMILES Code
CC1=NC2=C(C=CC(F)=C2F)C=C1OC3=C(C(F)=CC=C3)C(C)(C)O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 347.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: van Rhijn N, Storer ISR, Birch M, Oliver JD, Bottery MJ, Bromley MJ. Aspergillus fumigatus strains that evolve resistance to the agrochemical fungicide ipflufenoquin in vitro are also resistant to olorofim. Nat Microbiol. 2024 Jan;9(1):29-34. doi: 10.1038/s41564-023-01542-4. Epub 2023 Dec 27. PMID: 38151646; PMCID: PMC10769868. 2: Verweij PE, Arendrup MC, Alastruey-Izquierdo A, Gold JAW, Lockhart SR, Chiller T, White PL. Dual use of antifungals in medicine and agriculture: How do we help prevent resistance developing in human pathogens? Drug Resist Updat. 2022 Dec;65:100885. doi: 10.1016/j.drup.2022.100885. Epub 2022 Oct 20. PMID: 36283187; PMCID: PMC10693676.