Synonym
Sintofen; Cintofen;
IUPAC/Chemical Name
1-(4-chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid
InChi Key
QLMNCUHSDAGQGT-UHFFFAOYSA-N
InChi Code
1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)
SMILES Code
COCCOC1=C2C(=O)C(=NN(C3=CC=C(Cl)C=C3)C2=CC=C1)C(O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
374.78
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: European Food Safety Authority (EFSA); Brancato A, Brocca D, Carrasco Cabrera L, De Lentdecker C, Erdos Z, Ferreira L, Greco L, Jarrah S, Kardassi D, Leuschner R, Lostia A, Lythgo C, Medina P, Miron I, Molnar T, Pedersen R, Reich H, Sacchi A, Santos M, Stanek A, Sturma J, Tarazona J, Theobald A, Vagenende B, Villamar-Bouza L. Review of the existing maximum residue levels for sintofen according to Article 12 of Regulation (EC) No 396/2005. EFSA J. 2018 Aug 28;16(8):e05406. doi: 10.2903/j.efsa.2018.5406. PMID: 32626037; PMCID: PMC7009338.
2: Easterly AC, Stroup WW, Garst N, Belamkar V, Sarazin JB, Moittié T, Ibrahim AMH, Rudd JC, Souza E, Baenziger PS. Determining the Efficacy of a Hybridizing Agent in Wheat (Triticum aestivum L.). Sci Rep. 2019 Dec 27;9(1):20173. doi: 10.1038/s41598-019-56664-9. PMID: 31882883; PMCID: PMC6934762.
