HRO761 is a potent, selective, allosteric WRN inhibitor that binds at the interface of the D1 and D2 helicase domains, locking WRN in an inactive conformation.
MedKoo Cat#: 127223
Name: HRO761
CAS#: 2869954-34-5
Chemical Formula: C31H31ClF3N9O5
Exact Mass: 701.2089
Molecular Weight: 702.09
Elemental Analysis: C, 53.03; H, 4.45; Cl, 5.05; F, 8.12; N, 17.96; O, 11.39
The following data is based on the product molecular weight 702.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
