AKV-9 is a SOD1 inhibitor. AKV-9 nhibits SOD1-induced protein aggregation and exhibits protective efficacy against SOD1-induced cytotoxicity in PC-12. AKV-9 ameliorates amyotrophic lateral sclerosis in mouse models and extends their lifespan.
MedKoo Cat#: 145098
Name: AKV-9
CAS#: 1307262-15-2
Chemical Formula: C16H14F6O3
Exact Mass: 368.0847
Molecular Weight: 368.28
Elemental Analysis: C, 52.18; H, 3.83; F, 30.95; O, 13.03
The following data is based on the product molecular weight 368.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |