SDI-118 is a novel procognitive SV2A modulator. SDI-118 modulates the activity of synaptic vesicle glycoprotein 2A (SV2A) in the brain and shows cognitive enhancing effects in a range of animal models of cognitive deficit. Studies show that single oral doses of SDI-118 up to 80 mg were very well tolerated in healthy male animal subjects, showing its efficacy in aiding brains with cognitive disorders.
MedKoo Cat#: 145095
Name: SDI-118
CAS#: 1651179-19-9
Chemical Formula: C13H10ClF3N4O
Exact Mass: 330.0495
Molecular Weight: 330.70
Elemental Analysis: C, 47.22; H, 3.05; Cl, 10.72; F, 17.23; N, 16.94; O, 4.84
The following data is based on the product molecular weight 330.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
