EPM-301 is a Cannabidiolic Acid-Methyl Ester. EPM-301 demonstrated antidepressant-like effects in male rats, prompting exploration of its acute effects and underlying mechanisms in female rats using the Wistar-Kyoto (WKY) rat model of depression. Females required higher doses of CBDA-ME to induce antidepressant-like effects compared to males, with CB2 receptor antagonism blocking these effects in females but not in males.
MedKoo Cat#: 145063
Name: EPM-301
CAS#: 55658-71-4
Chemical Formula: C23H32O4
Exact Mass: 372.2301
Molecular Weight: 372.51
Elemental Analysis: C, 74.16; H, 8.66; O, 17.18
The following data is based on the product molecular weight 372.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
