MedKoo Cat#: 145051 | Name: 25CN-NBMD

Description:

WARNING: This product is for research use only, not for human or veterinary use.

25CN-NBMD is a highly selective agonist for the serotonin 5-HT2A receptor (5-HT2AR), and was developed as a pharmacological tool to explore 5-HT2AR expression and functions. Structural modifications at the 2' and 3' positions of 25CN-NBMD were investigated, revealing their crucial role in 5-HT2AR activity. 25CN-NBMD was effective in inducing characteristic responses associated with 5-HT2AR activation.

Chemical Structure

25CN-NBMD
25CN-NBMD
CAS#1391491-24-9

Theoretical Analysis

MedKoo Cat#: 145051

Name: 25CN-NBMD

CAS#: 1391491-24-9

Chemical Formula: C19H20N2O4

Exact Mass: 340.1423

Molecular Weight: 340.38

Elemental Analysis: C, 67.05; H, 5.92; N, 8.23; O, 18.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
25CN-NBMD; 25CN NBMD; 25CNNBMD;
IUPAC/Chemical Name
4-(2-((benzo[d][1,3]dioxol-4-ylmethyl)amino)ethyl)-2,5-dimethoxybenzonitrile
InChi Key
CFFGJOIVRPVLGJ-UHFFFAOYSA-N
InChi Code
1S/C19H20N2O4/c1-22-17-9-15(10-20)18(23-2)8-13(17)6-7-21-11-14-4-3-5-16-19(14)25-12-24-16/h3-5,8-9,21H,6-7,11-12H2,1-2H3
SMILES Code
COC1=CC(CCNCC2=C3OCOC3=CC=C2)=C(OC)C=C1C#N
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 340.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jensen AA, Halberstadt AL, Märcher-Rørsted E, Odland AU, Chatha M, Speth N, Liebscher G, Hansen M, Bräuner-Osborne H, Palner M, Andreasen JT, Kristensen JL. The selective 5-HT2A receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH. Biochem Pharmacol. 2020 Jul;177:113979. doi: 10.1016/j.bcp.2020.113979. Epub 2020 Apr 13. PMID: 32298690.