MedKoo Cat#: 145025 | Name: RM-5038

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RM-5038 is a halogeno-thiazolide. RM-5038 is a polypharmacology agent with at least three mechanisms of action against a broad spectrum of parasites, bacteria and viruses, and in respiratory viruses, they inhibit the replication of orthomyxoviridae and paramyxoviridae at a post-translational level.

Chemical Structure

RM-5038
RM-5038
CAS#1349090-91-0

Theoretical Analysis

MedKoo Cat#: 145025

Name: RM-5038

CAS#: 1349090-91-0

Chemical Formula: C12H9ClN2O3S

Exact Mass: 296.0022

Molecular Weight: 296.73

Elemental Analysis: C, 48.57; H, 3.06; Cl, 11.95; N, 9.44; O, 16.18; S, 10.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
RM-5038; RM 5038; RM5038
IUPAC/Chemical Name
2-((5-chlorothiazol-2-yl)carbamoyl)phenyl acetate
InChi Key
BVLLRNZKAURPNA-UHFFFAOYSA-N
InChi Code
1S/C12H9ClN2O3S/c1-7(16)18-9-5-3-2-4-8(9)11(17)15-12-14-6-10(13)19-12/h2-6H,1H3,(H,14,15,17)
SMILES Code
CC(=O)OC1=C(C=CC=C1)C(=O)NC2=NC=C(Cl)S2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 296.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Trabattoni D, Gnudi F, Ibba SV, Saulle I, Agostini S, Masetti M, Biasin M, Rossignol JF, Clerici M. Thiazolides Elicit Anti-Viral Innate Immunity and Reduce HIV Replication. Sci Rep. 2016 Jun 2;6:27148. doi: 10.1038/srep27148. PMID: 27250526; PMCID: PMC4890011. 2: Gargala G, François A, Favennec L, Rossignol JF. Activity of halogeno- thiazolides against Cryptosporidium parvum in experimentally infected immunosuppressed gerbils (Meriones unguiculatus). Antimicrob Agents Chemother. 2013 Jun;57(6):2821-3. doi: 10.1128/AAC.01538-12. Epub 2013 Mar 11. PMID: 23478972; PMCID: PMC3716183. 3: Stachulski AV, Swift K, Cooper M, Reynolds S, Norton D, Slonecker SD, Rossignol JF. Synthesis and pre-clinical studies of new amino-acid ester thiazolide prodrugs. Eur J Med Chem. 2017 Jan 27;126:154-159. doi: 10.1016/j.ejmech.2016.09.080. Epub 2016 Sep 26. PMID: 27750149; PMCID: PMC7125651.