MedKoo Cat#: 127109 | Name: Coumarin 478
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Coumarin 478 is a synthetic coumarin. It is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 10.7 and 27.8 µM, respectively).

Chemical Structure

Coumarin 478
Coumarin 478
CAS#41175-45-5

Theoretical Analysis

MedKoo Cat#: 127109

Name: Coumarin 478

CAS#: 41175-45-5

Chemical Formula: C18H19NO2

Exact Mass: 281.1416

Molecular Weight: 281.36

Elemental Analysis: C, 76.84; H, 6.81; N, 4.98; O, 11.37

Price and Availability

Size Price Availability Quantity
50mg USD 350.00 2 Weeks
100mg USD 550.00 2 Weeks
250mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
Coumarin 478; Coumarin 106; NSC 290434
IUPAC/Chemical Name
2,3,6,7,10,11-hexahydro-1H,5H-cyclopenta[4,5]pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-12(9H)-one
InChi Key
LLSRPENMALNOFW-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H19NO2/c20-18-13-6-1-5-12(13)15-10-11-4-2-8-19-9-3-7-14(16(11)19)17(15)21-18/h10H,1-9H2
SMILES Code
O=C1OC2=C(C3=C1CCC3)C=C4C5=C2CCCN5CCC4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 281.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL