MedKoo Cat#: 126815 | Name: E12CA1A3
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

E12CA1A3 is an ionizable cationic lipid (pKa = 6.4) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.

Chemical Structure

E12CA1A3
E12CA1A3
CAS#2778182-26-4

Theoretical Analysis

MedKoo Cat#: 126815

Name: E12CA1A3

CAS#: 2778182-26-4

Chemical Formula: C34H67NO4

Exact Mass: 553.5070

Molecular Weight: 553.91

Elemental Analysis: C, 73.73; H, 12.19; N, 2.53; O, 11.55

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 650.00 2 Weeks
10mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
E12CA1A3; E12CA1-A3; E12-CA1-A3; E12-CA1A3
IUPAC/Chemical Name
2-hexyl-decanoic acid, 2-[4-(dimethylamino)-1-oxobutoxy]dodecyl ester
InChi Key
PAPHCDVUAFOSMR-UHFFFAOYSA-N
InChi Code
InChI=1S/C34H67NO4/c1-6-9-12-15-17-18-20-23-27-32(39-33(36)28-24-29-35(4)5)30-38-34(37)31(25-21-14-11-8-3)26-22-19-16-13-10-7-2/h31-32H,6-30H2,1-5H3
SMILES Code
CCCCCCCCC(CCCCCC)C(OCC(OC(CCCN(C)C)=O)CCCCCCCCCC)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 553.91 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL