MedKoo Cat#: 126697 | Name: SEF31

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SEF31 is an NF-κB inhibitor.

Chemical Structure

SEF31
SEF31
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 126697

Name: SEF31

CAS#: N/A

Chemical Formula: C17H14N2OS

Exact Mass: 294.0827

Molecular Weight: 294.37

Elemental Analysis: C, 69.36; H, 4.79; N, 9.52; O, 5.43; S, 10.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
SEF-31; SEF 31; SEF31
IUPAC/Chemical Name
(3Z,5Z)-3,5-bis(pyridin-2-ylmethylene)tetrahydro-4H-thiopyran-4-one
InChi Key
SZUIRPWFHMMLIA-UTLPMFLDSA-N
InChi Code
InChI=1S/C17H14N2OS/c20-17-13(9-15-5-1-3-7-18-15)11-21-12-14(17)10-16-6-2-4-8-19-16/h1-10H,11-12H2/b13-9+,14-10+
SMILES Code
O=C(/C(CSC/1)=C/C2=NC=CC=C2)C1=C\C3=CC=CC=N3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 294.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Novel NF-κB Inhibitor-Conjugated Pt(IV) Prodrug to Enable Cancer Therapy through ROS/ER Stress and Mitochondrial Dysfunction and Overcome Multidrug Resistance Meng Wang, Guimei Li, Guiyang Jiang, Jinyuan Cai, Zhikun Liu, Rizhen Huang, Xiaochao Huang, and Hengshan Wang Journal of Medicinal Chemistry Article ASAP DOI: 10.1021/acs.jmedchem.3c02182