MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 126383 | Name: NBCoV63

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NBCoV63 is an S protein / ACE2 interaction inhibitor (IC50 = 55 nM).

Chemical Structure

NBCoV63
NBCoV63
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 126383

Name: NBCoV63

CAS#: N/A

Chemical Formula: C23H16N2O4S

Exact Mass: 416.0831

Molecular Weight: 416.45

Elemental Analysis: C, 66.34; H, 3.87; N, 6.73; O, 15.37; S, 7.70

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
NBCoV63; NBCoV-63; NBCoV 63
IUPAC/Chemical Name
(E)-3-(5-((6,7-dimethyl-3-oxobenzo[4,5]imidazo[2,1-b]thiazol-2(3H)-ylidene)methyl)furan-2-yl)benzoic acid
InChi Key
JUQGOGQMRRNBFF-RGVLZGJSSA-N
InChi Code
InChI=1S/C23H16N2O4S/c1-12-8-17-18(9-13(12)2)25-21(26)20(30-23(25)24-17)11-16-6-7-19(29-16)14-4-3-5-15(10-14)22(27)28/h3-11H,1-2H3,(H,27,28)/b20-11+
SMILES Code
O=C(/C(S1)=C\C(O2)=CC=C2C3=CC(C(O)=O)=CC=C3)N4C1=NC5=C4C=C(C)C(C)=C5
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 416.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Curreli F, Chau K, Tran TT, Nicolau I, Ahmed S, Das P, Hillyer CD, Premenko-Lanier M, Debnath AK. Discovery of Highly Potent Small Molecule Pan-Coronavirus Fusion Inhibitors. Viruses. 2023 Apr 19;15(4):1001. doi: 10.3390/v15041001. PMID: 37112982; PMCID: PMC10141620.