MedKoo Cat#: 126176 | Name: VL422
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

VL422 is an ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA for gene editing in vitro and in vivo.

Chemical Structure

VL422
VL422
CAS#2765519-47-7

Theoretical Analysis

MedKoo Cat#: 126176

Name: VL422

CAS#: 2765519-47-7

Chemical Formula: C62H117NO11

Exact Mass: 1051.8627

Molecular Weight: 1052.61

Elemental Analysis: C, 70.75; H, 11.20; N, 1.33; O, 16.72

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 850.00 2 Weeks
10mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
VL422; VL-422; VL 422
IUPAC/Chemical Name
O'1,O1-(2-((((3-(diethylamino)propoxy)carbonyl)oxy)methyl)propane-1,3-diyl) 8,8'-di(heptadecan-9-yl) di(octanedioate)
InChi Key
LUQLMJLIEUBIFP-UHFFFAOYSA-N
InChi Code
InChI=1S/C62H117NO11/c1-7-13-17-21-25-33-42-56(43-34-26-22-18-14-8-2)73-60(66)48-39-31-29-37-46-58(64)70-52-55(54-72-62(68)69-51-41-50-63(11-5)12-6)53-71-59(65)47-38-30-32-40-49-61(67)74-57(44-35-27-23-19-15-9-3)45-36-28-24-20-16-10-4/h55-57H,7-54H2,1-6H3
SMILES Code
CCCCCCCCC(CCCCCCCC)OC(CCCCCCC(OCC(COC(OCCCN(CC)CC)=O)COC(CCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)=O)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,052.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL