MedKoo Cat#: 126101 | Name: Chlormethazole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Chlormethazole (also known as Methazole) is an oxadiazolidine derivative and selective herbicide formerly used in Australia to control weeds in onions.

Chemical Structure

Chlormethazole
Chlormethazole
CAS#20354-26-1

Theoretical Analysis

MedKoo Cat#: 126101

Name: Chlormethazole

CAS#: 20354-26-1

Chemical Formula: C9H6Cl2N2O3

Exact Mass: 259.9755

Molecular Weight: 261.06

Elemental Analysis: C, 41.41; H, 2.32; Cl, 27.16; N, 10.73; O, 18.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Methazole; Probe; 20354-26-1; Oxydiazol; Bioxone
IUPAC/Chemical Name
2-(3,4-dichlorophenyl)-4-methyl-1,2,4-oxadiazolidine-3,5-dione
InChi Key
LRUUNMYPIBZBQH-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H6Cl2N2O3/c1-12-8(14)13(16-9(12)15)5-2-3-6(10)7(11)4-5/h2-4H,1H3
SMILES Code
CN1C(=O)ON(C1=O)C2=CC(Cl)=C(Cl)C=C2
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 261.06 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gregg E, Akhter I. Chlormethiazole abuse. Br J Psychiatry. 1979 Jun;134:627-9. doi: 10.1192/bjp.134.6.627. PMID: 476374. 2: McInnes GT. Chlormethiazole and alcohol: a lethal cocktail. Br Med J (Clin Res Ed). 1987 Mar 7;294(6572):592. doi: 10.1136/bmj.294.6572.592. PMID: 3103815; PMCID: PMC1245638. 3: Illingworth RN, Stewart MJ, Jarvie DR. Poisoning with chlormethiazole. Br Med J. 1980 Jan 5;280(6206):47-8. doi: 10.1136/bmj.280.6206.47-b. PMID: 7357271; PMCID: PMC1600485. 4: McInnes GT, Young RE. Poisoning with chlormethiazole. Br Med J. 1980 Jan 5;280(6206):47. doi: 10.1136/bmj.280.6206.47-a. PMID: 7357270; PMCID: PMC1600521. 5: Wilby MJ, Hutchinson PJ. The pharmacology of chlormethiazole: a potential neuroprotective agent? CNS Drug Rev. 2004 Winter;10(4):281-94. doi: 10.1111/j.1527-3458.2004.tb00028.x. PMID: 15592579; PMCID: PMC6741715. 6: Glatt MM. Chlormethiazole addiction. Br Med J. 1978 Sep 23;2(6141):894-5. doi: 10.1136/bmj.2.6141.894-b. PMID: 709111; PMCID: PMC1607962. 7: STALLWORTHY J. TO-DAY'S DRUGS. CHLORMETHIAZOLE. Br Med J. 1964 Jul 18;2(5402):171. PMID: 14150896; PMCID: PMC1816116. 8: Fulton B, Park GR. Intravenous chlormethiazole. Br J Hosp Med. 1992 Dec 2-1993 Jan 5;48(11):742-7. PMID: 1467819. 9: Oswald I, Adam K. Chlormethiazole and temazepam. Br Med J. 1980 Mar 22;280(6217):860-1. doi: 10.1136/bmj.280.6217.860-b. PMID: 6102879; PMCID: PMC1601027. 10: Briggs RS, Castleden M, Kraft CA. Chlormethiazole and temazepam. Br Med J. 1980 Apr 19;280(6221):1085-6. doi: 10.1136/bmj.280.6221.1085-c. PMID: 6104528; PMCID: PMC1601219.