Dimethylglycine | N,N-dimethylglycine | dimethylglycine | DMG | amino acid derivative | CAS#1118-68-9

MedKoo Cat#: 126041 | Name: Dimethylglycine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

N,N-dimethylglycine or dimethylglycine (DMG) is an amino acid derivative found in the cells of all plants and animals and can be obtained in the diet in small amounts from grains and meat.

Chemical Structure

Dimethylglycine

CAS#1118-68-9

Theoretical Analysis

MedKoo Cat#: 126041

Name: Dimethylglycine

CAS#: 1118-68-9

Chemical Formula: C4H9NO2

Exact Mass: 103.0633

Molecular Weight: 103.12

Elemental Analysis: C, 46.59; H, 8.80; N, 13.58; O, 31.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

N,N-dimethylglycine; dimethylglycine; 2-(dimethylamino)acetic acid; (Dimethylamino)acetic acid;

IUPAC/Chemical Name

dimethylglycine

InChi Key

FFDGPVCHZBVARC-UHFFFAOYSA-N

InChi Code

InChI=1S/C4H9NO2/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7)

SMILES Code

CN(C)CC(O)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 103.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dhanjal DS, Bhardwaj S, Chopra C, Singh R, Patocka J, Plucar B, Nepovimova E, Valis M, Kuca K. Millennium Nutrient N,N-Dimethylglycine (DMG) and its Effectiveness in Autism Spectrum Disorders. Curr Med Chem. 2022;29(15):2632-2651. doi: 10.2174/0929867328666211125091811. PMID: 34823458. 2: Herbert V. N,N-dimethylglycine for epilepsy. N Engl J Med. 1983 Mar 3;308(9):527-8. doi: 10.1056/NEJM198303033080918. PMID: 6185843. 3: Tonda ME, Hart LL. N,N dimethylglycine and L-carnitine as performance enhancers in athletes. Ann Pharmacother. 1992 Jul-Aug;26(7-8):935-7. PMID: 1380344. 4: Koga T, Inoue K, Hirayama F, Hiromura M, Fujii K, Ishii Y, Hirao-Suzuki M, Takeda S, Toda A, Soeda F. Dimethylglycine, a Methionine Metabolite, Participates in the Suppressive Effect of Methionine on 1-Fluoro-2,4-dinitrobenzene-Induced Dermatitis. Biol Pharm Bull. 2023 Jul 1;46(7):946-954. doi: 10.1248/bpb.b23-00098. Epub 2023 May 13. PMID: 37183024. 5: Hu Y, Liu X, Ekpo MD, Chen J, Chen X, Zhang W, Zhao R, Xie J, He Y, Tan S. Dimethylglycine Can Enhance the Cryopreservation of Red Blood Cells by Reducing Ice Formation and Oxidative Damage. Int J Mol Sci. 2023 Apr 3;24(7):6696. doi: 10.3390/ijms24076696. PMID: 37047668; PMCID: PMC10095525. 6: Yao H, Hu Y, Tong H, Shi S. Dimethylglycine Alleviates Metabolic Dysfunction- Associated Fatty Liver Disease by Improving the Circulating Estrogen Level via Gut Staphylococcus. J Agric Food Chem. 2023 Dec 22. doi: 10.1021/acs.jafc.3c07075. Epub ahead of print. PMID: 38131116. 7: Porter DH, Cook RJ, Wagner C. Enzymatic properties of dimethylglycine dehydrogenase and sarcosine dehydrogenase from rat liver. Arch Biochem Biophys. 1985 Dec;243(2):396-407. doi: 10.1016/0003-9861(85)90516-8. PMID: 2417560.