Synonym
dulcitol; galactitol; 608-66-2; dulcite; Euonymit;
IUPAC/Chemical Name
(2R,3S,4R,5S)-hexane-1,2,3,4,5,6-hexaol
InChi Key
FBPFZTCFMRRESA-GUCUJZIJSA-N
InChi Code
InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6-
SMILES Code
OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
182.17
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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32989517.
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6: Yager CT, Chen J, Reynolds R, Segal S. Galactitol and galactonate in red
blood cells of galactosemic patients. Mol Genet Metab. 2003 Nov;80(3):283-9.
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7: Nolle N, Felsl A, Heermann R, Fuchs TM. Genetic Characterization of the
Galactitol Utilization Pathway of Salmonella enterica Serovar Typhimurium. J
Bacteriol. 2017 Jan 30;199(4):e00595-16. doi: 10.1128/JB.00595-16. PMID:
27956522; PMCID: PMC5287402.
8: Kohlmeier MG, White CE, Fowler JE, Finan TM, Oresnik IJ. Galactitol
catabolism in Sinorhizobium meliloti is dependent on a chromosomally encoded
sorbitol dehydrogenase and a pSymB-encoded operon necessary for tagatose
catabolism. Mol Genet Genomics. 2019 Jun;294(3):739-755. doi:
10.1007/s00438-019-01545-z. Epub 2019 Mar 16. PMID: 30879203.
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biochemical status in children with Duarte galactosemia: utility of galactose,
galactitol, galactonate, and galactose 1-phosphate. Clin Chem. 2010
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20489133.
10: Yager C, Ning C, Reynolds R, Leslie N, Segal S. Galactitol and galactonate
accumulation in heart and skeletal muscle of mice with deficiency of
galactose-1-phosphate uridyltransferase. Mol Genet Metab. 2004 Feb;81(2):105-11.
doi: 10.1016/j.ymgme.2003.10.001. PMID: 14741191.
