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MedKoo Cat#: 125817 | Name: SF001

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SF001 is an experimental antifungal drug based on amphotericin B (AmB) that is engineered to be less toxic to the kidneys

Chemical Structure

SF001
SF001
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 125817

Name: SF001

CAS#: N/A

Chemical Formula: C50H80N2O18

Exact Mass: 996.5400

Molecular Weight: 997.19

Elemental Analysis: C, 60.22; H, 8.09; N, 2.81; O, 28.88

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
SF001; SF-001; SF 001; AM-2 19; AM 2-19; AM-2-19;
IUPAC/Chemical Name
(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2S,3S,4R,5R,6S)-4-amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-N-(1,3-dihydroxypropan-2-yl)-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxamide
InChi Key
DYFDQVUOYRWTOB-VVSZBRONSA-N
InChi Code
InChI=1S/C50H80N2O18/c1-29-17-15-13-11-9-7-5-6-8-10-12-14-16-18-37(69-49-47(64)44(51)46(63)32(4)68-49)24-41-43(48(65)52-33(27-53)28-54)40(60)26-50(66,70-41)25-36(57)22-39(59)38(58)20-19-34(55)21-35(56)23-42(61)67-31(3)30(2)45(29)62/h5-18,29-41,43-47,49,53-60,62-64,66H,19-28,51H2,1-4H3,(H,52,65)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t29-,30-,31-,32-,34+,35+,36-,37-,38+,39+,40-,41-,43+,44+,45+,46-,47-,49+,50+/m0/s1
SMILES Code
C[C@@H]([C@H](C)OC(C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C1)=O)[C@H](O)[C@@H](C)/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](O[C@@H]2[C@@H](O)[C@H](N)[C@@H](O)[C@H](C)O2)C[C@H]3[C@H](C(NC(CO)CO)=O)[C@@H](O)C[C@]1(O)O3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 997.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
EFSA Panel name on Food Additives and Flavourings (FAF); Younes M, Aquilina G, Castle L, Degen G, Engel KH, Fowler PJ, Frutos Fernandez MJ, Fürst P, Gundert-Remy U, Gürtler R, Husøy T, Manco M, Moldeus P, Passamonti S, Shah R, Waalkens-Berendsen I, Wright M, Benigni R, Boon P, Bolognesi C, Cordelli E, Chipman K, Sahlin U, Carfì M, Halamoda B, Mech A, Martino C, Multari S, Palaniappan V, Tard A, Mennes W. Scientific opinion on the renewal of the authorisation of proFagus Smoke R714 (SF-001) as a smoke flavouring Primary Product. EFSA J. 2023 Nov 16;21(11):e08363. doi: 10.2903/j.efsa.2023.8363. PMID: 38027451; PMCID: PMC10652307.