MedKoo Cat#: 125740 | Name: N-acetyl-beta-neuraminic acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sodium aceneuramate is a sodium salt of aceneuramic acid (sialic acid). It is an effective inhalant expectorant. Inhalation of sodium aceneuramate repaired inflammation in the airway, and caused bronchitic rabbits to produce sputa with a low viscosity, similar to normal air-way secretions.

Chemical Structure

N-acetyl-beta-neuraminic acid
N-acetyl-beta-neuraminic acid
CAS#19342-33-7

Theoretical Analysis

MedKoo Cat#: 125740

Name: N-acetyl-beta-neuraminic acid

CAS#: 19342-33-7

Chemical Formula: C11H19NO9

Exact Mass: 309.1100

Molecular Weight: 309.27

Elemental Analysis: C, 42.72; H, 6.19; N, 4.53; O, 46.56

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
131-48-6; N-acetyl-beta-neuraminic acid; N-acetylneuramic acid; N-Acetyl-D-neuraminic acid; Lactaminic acid
IUPAC/Chemical Name
(2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid
InChi Key
SQVRNKJHWKZAKO-PFQGKNLYSA-N
InChi Code
InChI=1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11-/m0/s1
SMILES Code
[H][C@]1(O[C@@](O)(C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CO
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 309.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Martin JE, Tanenbaum SW, Flashner M. A facile procedure for the isolation of N-acetylneuramic acid from edible bird's-nest. Carbohydr Res. 1977 Jul;56(2):423-5. doi: 10.1016/s0008-6215(00)83368-6. PMID: 561659. 2: Torres Gallardo J, Luna Lagunes RM, Sánchez Castillo J, Villalobos Ramírez M. Cambios diferenciales en los niveles séricos del acido N-acetilneuramínico y de la L-fucosa como manifestaciones de adaptación fisiológica y fisiopatológica en el humano. La gestación como modelo experimental. Los padecimientos tumorales, vasculares y hepáticos como posibles modelos patológicos [Differential changes in serum levels of N-acetylneuramic acid and L-fucose as manifestations of physiological and physiopathological adaptation in man. Pregnancy as an experimental model. The tumoral, vascular and hepatic diseases as possible pathological models]. Prensa Med Mex. 1976 May-Jun;41(5-6):144-8. Spanish. PMID: 1033543. 3: Lakhiari H, Muller D, Jozefonvicz J. Interaction mechanisms between insulin and N-acetylneuraminic acid in affinity chromatography. J Chromatogr A. 1995 Sep 8;711(1):93-103. doi: 10.1016/0021-9673(95)00189-t. PMID: 7496498. 4: Apicella MA, Coffin J, Ketterer M, Post DMB, Day CJ, Jen FE, Jennings MP. Nontypeable Haemophilus influenzae Lipooligosaccharide Expresses a Terminal Ketodeoxyoctanoate In Vivo, Which Can Be Used as a Target for Bactericidal Antibody. mBio. 2018 Jul 31;9(4):e01401-18. doi: 10.1128/mBio.01401-18. PMID: 30065093; PMCID: PMC6069110.