MedKoo Cat#: 125659 | Name: 3-hydroxydesloratadine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

The glucuronide conjugate of 3-hydroxydesloratadine is the major metabolite of desloratadine in human plasma and urine.

Chemical Structure

3-hydroxydesloratadine
3-hydroxydesloratadine
CAS#119410-08-1

Theoretical Analysis

MedKoo Cat#: 125659

Name: 3-hydroxydesloratadine

CAS#: 119410-08-1

Chemical Formula: C19H19ClN2O

Exact Mass: 326.1200

Molecular Weight: 326.82

Elemental Analysis: C, 69.83; H, 5.86; Cl, 10.85; N, 8.57; O, 4.90

Price and Availability

Size Price Availability Quantity
25mg USD 650.00 2 Weeks
50mg USD 1,150.00 2 Weeks
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Related CAS #
No Data
Synonym
3-hydroxydesloratadine; 3-Hydroxy Desloratadine; SCH 45581; SCH45581; SCH-45581
IUPAC/Chemical Name
8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol
InChi Key
NDFMTPISBHBIKE-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H19ClN2O/c20-15-3-4-17-13(9-15)1-2-14-10-16(23)11-22-19(14)18(17)12-5-7-21-8-6-12/h3-4,9-11,21,23H,1-2,5-8H2
SMILES Code
OC1=CN=C2C(CCC3=C(C=CC(Cl)=C3)C2=C4CCNCC4)=C1
Appearance
To be determined
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 326.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Ghosal A, Yuan Y, Hapangama N, Su AD, Alvarez N, Chowdhury SK, Alton KB, Patrick JE, Zbaida S. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of 3-hydroxydesloratadine. Biopharm Drug Dispos. 2004 Sep;25(6):243-52. doi: 10.1002/bdd.405. PMID: 15334623.