RM-2 Ga-68 | CAS#1444870-03-4 | radioconjugate | GRPR | PET/CT

MedKoo Cat#: 125509 | Name: RM-2 Ga-68

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Gallium Ga 68-labeled RM2 is a radioconjugate containing a synthetic bombesin receptor antagonist targeting the gastrin-releasing peptide receptor (GRPR), that is linked by the macrocyclic chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) to the radionuclide gallium (Ga) 68, with potential use in diagnostic imaging using positron emission tomography/computed tomography (PET/CT).

Chemical Structure

RM-2 Ga-68

CAS#1444870-03-4

Theoretical Analysis

MedKoo Cat#: 125509

Name: RM-2 Ga-68

CAS#: 1444870-03-4

Chemical Formula: C78H11568GaN20O19

Exact Mass: 1703.7900

Molecular Weight: 1704.83

Elemental Analysis: C, 54.95; H, 6.80; Ga, 3.98; N, 16.43; O, 17.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NPI2H5M36D; 68Ga-RM2; Bombesin (68Ga); (68Ga)-RM2; RM-2 Ga-68

IUPAC/Chemical Name

gallium-68Ga 2,2',2''-(10-(2-((1-((4R,7S,10S,13S,16S,22S,25S,26S,30S)-22-((1H-imidazol-4-yl)methyl)-10-((1H-indol-3-yl)methyl)-7-(3-amino-3-oxopropyl)-4-benzyl-30-carbamoyl-26-hydroxy-25-isobutyl-16-isopropyl-13,32-dimethyl-2,5,8,11,14,17,20,23,28-nonaoxo-3,6,9,12,15,18,21,24,29-nonaazatritriacontyl)piperidin-4-yl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate

InChi Key

HPQFXKMKTOABLV-OACIABJLSA-K

InChi Code

InChI=1S/C78H118N20O19.Ga/c1-46(2)31-57(62(99)36-64(101)87-58(72(80)111)32-47(3)4)91-77(116)61(35-53-38-81-45-84-53)88-65(102)39-83-78(117)71(48(5)6)93-73(112)49(7)85-75(114)60(34-51-37-82-55-16-12-11-15-54(51)55)92-74(113)56(17-18-63(79)100)90-76(115)59(33-50-13-9-8-10-14-50)89-67(104)41-94-21-19-52(20-22-94)86-66(103)40-95-23-25-96(42-68(105)106)27-29-98(44-70(109)110)30-28-97(26-24-95)43-69(107)108;/h8-16,37-38,45-49,52,56-62,71,82,99H,17-36,39-44H2,1-7H3,(H2,79,100)(H2,80,111)(H,81,84)(H,83,117)(H,85,114)(H,86,103)(H,87,101)(H,88,102)(H,89,104)(H,90,115)(H,91,116)(H,92,113)(H,93,112)(H,105,106)(H,107,108)(H,109,110);/q;+3/p-3/t49-,56-,57-,58-,59+,60-,61-,62-,71-;/m0./s1/i;1-2

SMILES Code

[68Ga+3].CC(C)C[C@H](NC(=O)[C@H](CC1=CNC=N1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CC4=CC=CC=C4)NC(=O)CN5CCC(CC5)NC(=O)CN6CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC6)C(C)C)[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(N)=O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,704.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.