Balamapimod, also known as MKI-822, is a Ras/Raf/MEK inhibitor. Balamapimod, may be potentially useful for the treatment or inhibition of certain diseases that are the result of deregulation of Ras/Raf/MEK protein kinases. In addition, Balamapimod may be also useful for the treatment and inhibition of stroke, osteoporosis, rheumatoid arthritis and other inflammatory disorders, as well as polycystic kidney disease and colonic polyps.
MedKoo Cat#: 201922
Name: Balamapimod (MKI-833)
CAS#: 863029-99-6
Chemical Formula: C30H32ClN7OS
Exact Mass: 573.2078
Molecular Weight: 574.14
Elemental Analysis: C, 62.76; H, 5.62; Cl, 6.17; N, 17.08; O, 2.79; S, 5.58
The following data is based on the product molecular weight 574.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
