MedKoo Cat#: 125445 | Name: Cytidine triphosphate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CTP is a pyrimidine ribonucleoside 5'-triphosphate and a cytidine 5'-phosphate. It has a role as an Escherichia coli metabolite and a mouse metabolite.

Chemical Structure

Cytidine triphosphate
Cytidine triphosphate
CAS#65-47-4

Theoretical Analysis

MedKoo Cat#: 125445

Name: Cytidine triphosphate

CAS#: 65-47-4

Chemical Formula: C9H16N3O14P3

Exact Mass: 482.9800

Molecular Weight: 483.16

Elemental Analysis: C, 22.37; H, 3.34; N, 8.70; O, 46.36; P, 19.23

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Cytidine triphosphate; cytidine-5'-triphosphate; 65-47-4; Cytidine 5'-(tetrahydrogen triphosphate); Cytidine 5'-triphosphate
IUPAC/Chemical Name
((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
InChi Key
PCDQPRRSZKQHHS-XVFCMESISA-N
InChi Code
InChI=1S/C9H16N3O14P3/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
SMILES Code
NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 483.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhu M, Sun W, Wang Y, Meng J, Zhang D, Guo T, Ouyang P, Ying H, Xie J. Engineered cytidine triphosphate synthetase with reduced product inhibition. Protein Eng Des Sel. 2014 Jul;27(7):225-33. doi: 10.1093/protein/gzu019. Epub 2014 Jun 5. PMID: 24902851. 2: Jalal AS, Tran NT, Le TB. ParB spreading on DNA requires cytidine triphosphate in vitro. Elife. 2020 Feb 20;9:e53515. doi: 10.7554/eLife.53515. PMID: 32077854; PMCID: PMC7053999. 3: Long C, Koshland DE Jr. Cytidine triphosphate synthetase. Methods Enzymol. 1978;51:79-83. doi: 10.1016/s0076-6879(78)51014-8. PMID: 357909. 4: van den Berg AA, van Lenthe H, Kipp JB, de Korte D, van Kuilenburg AB, van Gennip AH. Cytidine triphosphate (CTP) synthetase activity during cell cycle progression in normal and malignant T-lymphocytic cells. Eur J Cancer. 1995;31A(1):108-12. doi: 10.1016/0959-8049(94)00442-8. PMID: 7695960.