Synonym
F7H inhibitor; F7-H inhibitor; F-7H inhibitor; F-7-H inhibitor; F7-H; F-7H; F-7-H; F7H
IUPAC/Chemical Name
4-fluoro-N-(4-((2-oxo-2-((4-phenylthiazol-2-yl)amino)ethyl)thio)phenyl)benzamide
InChi Key
GEURGPJRAOYJKC-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H18FN3O2S2/c25-18-8-6-17(7-9-18)23(30)26-19-10-12-20(13-11-19)31-15-22(29)28-24-27-21(14-32-24)16-4-2-1-3-5-16/h1-14H,15H2,(H,26,30)(H,27,28,29)
SMILES Code
O=C(C1=CC=C(C=C1)F)NC2=CC=C(C=C2)SCC(NC3=NC(C4=CC=CC=C4)=CS3)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
463.55
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Li C, Wu Y, Wang W, Xu L, Zhou Y, Yue Y, Wu T, Yang M, Qiu Y, Huang M, Zhou
F, Zhou Y, Hao P, Lin Z, Wang MW, Zhao S, Yang D, Xu F, Tao H. Structure-Based
Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7. J
Med Chem. 2023 Sep 14;66(17):11855-11868. doi: 10.1021/acs.jmedchem.2c01795.
Epub 2023 Sep 5. PMID: 37669317.
2: Diaba SY, Anafo T, Tetteh LA, Oyibo MA, Alola AA, Shafie-Khah M, Elmusrati M.
SCADA securing system using deep learning to prevent cyber infiltration. Neural
Netw. 2023 Aug;165:321-332. doi: 10.1016/j.neunet.2023.05.047. Epub 2023 Jun 2.
PMID: 37327579.
