Synonym
19-Norandrosterone; 1225-01-0; 19-Noreoiandrosterone; 5alpha-Estran-3alpha-ol-17-one; 3alpha-hydroxy-5alpha-estran-17-one
IUPAC/Chemical Name
(3R,5S,8R,9R,10S,13S,14S)-3-hydroxy-13-methyl-2,3,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-1H-cyclopenta[a]phenanthren-17-one
InChi Key
UOUIARGWRPHDBX-CQZDKXCPSA-N
InChi Code
InChI=1S/C18H28O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h11-16,19H,2-10H2,1H3/t11-,12+,13-,14+,15+,16-,18-/m0/s1
SMILES Code
O=C1CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@H](O)CC[C@]4([H])[C@@]3([H])CC[C@]12C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
276.42
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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Sports Med. 2006 Jul;40 Suppl 1(Suppl 1):i25-9. doi: 10.1136/bjsm.2006.028027.
PMID: 16799098; PMCID: PMC2657496.
2: Hülsemann F, Fußhöller G, Lehn C, Thevis M. Excretion of 19-norandrosterone
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abuse of 19-norsteroids in doping controls: A new gas chromatography coupled to
isotope ratio mass spectrometry method for the analysis of 19-norandrosterone
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athlete's drug testing. Steroids. 2009 Mar;74(3):359-64. doi:
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endogenous 19-norandrosterone in human urine. J Chromatogr B Biomed Sci Appl.
1999 Feb 19;723(1-2):157-72. doi: 10.1016/s0378-4347(98)00541-6. PMID: 10080643.
6: Tseng YL, Kuo FH, Sun KH. Quantification and profiling of 19-norandrosterone
and 19-noretiocholanolone in human urine after consumption of a nutritional
supplement and norsteroids. J Anal Toxicol. 2005 Mar;29(2):124-34. doi:
10.1093/jat/29.2.124. PMID: 15902981.
7: Björkhem I, Ek H. Detection and quantitation of 19-norandrosterone in urine
by isotope dilution-mass spectrometry. J Steroid Biochem. 1982 Oct;17(4):447-51.
doi: 10.1016/0022-4731(82)90640-9. PMID: 7132356.
8: De Wasch K, Le Bizec B, De Brabander H, André F, Impens S. Consequence of
boar edible tissue consumption on urinary profiles of nandrolone metabolites.
II. Identification and quantification of 19-norsteroids responsible for
19-norandrosterone and 19-noretiocholanolone excretion in human urine. Rapid
Commun Mass Spectrom. 2001;15(16):1442-7. doi: 10.1002/rcm.391. PMID: 11507757.
9: Palermo A, Alessi B, Botrè F, de la Torre X, Fiacco I, Mazzarino M. In vitro
evaluation of the effects of anti-fungals, benzodiazepines and non-steroidal
anti-inflammatory drugs on the glucuronidation of 19-norandrosterone:
implications on doping control analysis. Drug Test Anal. 2016 Sep;8(9):930-9.
doi: 10.1002/dta.1897. Epub 2015 Oct 20. PMID: 26480899.
