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MedKoo Cat#: 125253 | Name: TRO-40303

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TRO-40303, a new cardioprotective compound, inhibits mitochondrial permeability transition.

Chemical Structure

TRO-40303
TRO-40303
CAS#14291-24-8

Theoretical Analysis

MedKoo Cat#: 125253

Name: TRO-40303

CAS#: 14291-24-8

Chemical Formula: C26H47NO2

Exact Mass: 405.3600

Molecular Weight: 405.67

Elemental Analysis: C, 76.98; H, 11.68; N, 3.45; O, 7.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
tro40303; TRO-40303; TRO 40303; 3W389841RN; 3,5-Seco-4-norcholestan-5-one oxime-3-ol
IUPAC/Chemical Name
(3R,3aR,5aS,6R,9aS,9bS,E)-6-(3-hydroxypropyl)-3a,6-dimethyl-3-((R)-6-methylheptan-2-yl)dodecahydro-7H-cyclopenta[a]naphthalen-7-one oxime
InChi Key
OBKBVSFXEIFOMS-YVABUZGXSA-N
InChi Code
InChI=1S/C26H47NO2/c1-18(2)8-6-9-19(3)21-11-12-22-20-10-13-24(27-29)26(5,15-7-17-28)23(20)14-16-25(21,22)4/h18-23,28-29H,6-17H2,1-5H3/b27-24+/t19-,20+,21-,22+,23+,25-,26-/m1/s1
SMILES Code
CC(CCC[C@@]([C@@]1([H])CC[C@@]2([H])[C@]([C@]([C@@](CCCO)/3C)([H])CC[C@]12C)([H])CCC3=N/O)([H])C)C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 405.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Schaller S, Paradis S, Ngoh GA, Assaly R, Buisson B, Drouot C, Ostuni MA, Lacapere JJ, Bassissi F, Bordet T, Berdeaux A, Jones SP, Morin D, Pruss RM. TRO40303, a new cardioprotective compound, inhibits mitochondrial permeability transition. J Pharmacol Exp Ther. 2010 Jun;333(3):696-706. doi: 10.1124/jpet.110.167486. Epub 2010 Mar 9. PMID: 20215409.