P-943 C-11 | CAS#898807-42-6 | radioligand | PET

MedKoo Cat#: 125247 | Name: P-943 C-11

Description:

WARNING: This product is for research use only, not for human or veterinary use.

[(11)C]P943 is a new radioligand recently developed to image and quantify serotonin 5-Hydroxytryptamine (5-HT(1B)) receptors with positron emission tomography (PET)

Chemical Structure

P-943 C-11

CAS#898807-42-6

Theoretical Analysis

MedKoo Cat#: 125247

Name: P-943 C-11

CAS#: 898807-42-6

Chemical Formula: C26H35N3O2

Exact Mass: 421.2700

Molecular Weight: 421.59

Elemental Analysis: C, 74.07; H, 8.37; N, 9.97; O, 7.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

[(11)C]P943; N1RS162V1C; UNII-N1RS162V1C; (11C)P-943; P-943 C-11; (3R)-1-(4-(1-Methoxy-1-methyl-ethyl)phenyl)-3-((2-(4-methylpiperazin-1-yl)phenyl)methyl)pyrrolidin-2-one

IUPAC/Chemical Name

1-(4-(2-methoxypropan-2-yl)phenyl)-3-(2-(4-methylpiperazin-1-yl)benzyl)pyrrolidin-2-one

InChi Key

YGQWVNMSNMDPFQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H35N3O2/c1-26(2,31-4)22-9-11-23(12-10-22)29-14-13-21(25(29)30)19-20-7-5-6-8-24(20)28-17-15-27(3)16-18-28/h5-12,21H,13-19H2,1-4H3

SMILES Code

CC(C)(C1=CC=C(C=C1)N2CCC(C2=O)CC3=CC=CC=C3N4CCN(CC4)C)OC

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 421.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Gallezot JD, Nabulsi N, Neumeister A, Planeta-Wilson B, Williams WA, Singhal T, Kim S, Maguire RP, McCarthy T, Frost JJ, Huang Y, Ding YS, Carson RE. Kinetic modeling of the serotonin 5-HT(1B) receptor radioligand [(11)C]P943 in humans. J Cereb Blood Flow Metab. 2010 Jan;30(1):196-210. doi: 10.1038/jcbfm.2009.195. Epub 2009 Sep 23. PMID: 19773803; PMCID: PMC2949107.