FD-2157 is a photosensitive PI3K inhibitor. FD2157 exhibited remarkably enhanced anticancer activity in inhibition of PI3K pathway against melanoma cell lines upon light irradiation (4 min). Hence, this photosensitive PI3K inhibitor FD2157 may represent a valuable tool compound for studying the PI3K pathway and further optimization toward light-triggered cancer treatment.
MedKoo Cat#: 124993
Name: FD2157
CAS#: N/A
Chemical Formula: C27H21ClN6O8S
Exact Mass: 624.0800
Molecular Weight: 625.01
Elemental Analysis: C, 51.89; H, 3.39; Cl, 5.67; N, 13.45; O, 20.48; S, 5.13
The following data is based on the product molecular weight 625.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
