MedKoo Cat#: 124948 | Name: Lipid OA2
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lipid OA2 is an ionizable lipid which can form single component lipid nanoparticles (LNPs) for delivery of RNA.

Chemical Structure

Lipid OA2
Lipid OA2
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 124948

Name: Lipid OA2

CAS#: N/A

Chemical Formula: C47H91Cl2N3O5

Exact Mass: 847.6300

Molecular Weight: 849.16

Elemental Analysis: C, 66.48; H, 10.80; Cl, 8.35; N, 4.95; O, 9.42

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
25mg USD 650.00 2 Weeks
100mg USD 1,350.00 2 Weeks
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Related CAS #
No Data
Synonym
Lipid OA2; Lipid-OA-2; Lipid-OA2
IUPAC/Chemical Name
di((Z)-octadec-9-en-1-yl) L-lysyl-L-glutamate dihydrochloride
InChi Key
DBWZQQDZKDSHKF-CTLKWHTASA-N
InChi Code
InChI=1S/C47H89N3O5.2ClH/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35-41-54-45(51)39-38-44(50-46(52)43(49)37-33-34-40-48)47(53)55-42-36-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;;/h17-20,43-44H,3-16,21-42,48-49H2,1-2H3,(H,50,52);2*1H/b19-17-,20-18-;;/t43-,44-;;/m0../s1
SMILES Code
NCCCC[C@H](N)C(N[C@@H](CCC(OCCCCCCCC/C=C\CCCCCCCC)=O)C(OCCCCCCCC/C=C\CCCCCCCC)=O)=O.Cl.Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 849.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yu Z, Wu M, Huang Y, Wang Y, Chen Y, Long Q, Lin Z, Xue L, Ju C, Zhang C. Single-component lipid nanoparticles for engineering SOCS1 gene-silenced dendritic cells to boost tumor immunotherapy. Biomater Sci. 2022 Dec 20;11(1):263-277. doi: 10.1039/d2bm01549h. PMID: 36440740.