Synonym
CYSTEINYL-SULFONATED-DGN-549C; IMGN-632-CYSTEINYL-TOXIN CONJUGATE;
IUPAC/Chemical Name
S-(1-(2-(6-(((2S)-1-(((2S)-1-((3-((((S)-8-methoxy-6-oxo-11,12,12a,13-tetrahydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-9-yl)oxy)methyl)-5-((((12aS)-8-methoxy-6-oxo-12-sulfo-11,12,12a,13-tetrahydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-9-yl)oxy)methyl)phenyl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)amino)-6-oxohexanamido)ethyl)-2,5-dioxopyrrolidin-3-yl)-L-cysteine
InChi Key
HUBDXLAQPUOLNZ-XODFGUIKSA-N
InChi Code
InChI=1S/C63H70N10O17S2/c1-33(67-55(75)16-10-9-15-54(74)65-17-18-71-56(76)28-53(62(71)81)91-32-43(64)63(82)83)57(77)68-34(2)58(78)69-39-20-35(30-89-51-26-44-41(24-49(51)87-3)60(79)72-40(29-66-44)22-37-11-5-7-13-46(37)72)19-36(21-39)31-90-52-27-45-42(25-50(52)88-4)61(80)73-47-14-8-6-12-38(47)23-48(73)59(70-45)92(84,85)86/h5-8,11-14,19-21,24-27,33-34,40,43,48,53,59,66,70H,9-10,15-18,22-23,28-32,64H2,1-4H3,(H,65,74)(H,67,75)(H,68,77)(H,69,78)(H,82,83)(H,84,85,86)/t33-,34-,40-,43-,48-,53?,59?/m0/s1
SMILES Code
[H][C@@]12CC3=CC=CC=C3N1C(=O)C4=C(NC2)C=C(OCC5=CC(COC6=CC7=C(C=C6OC)C(=O)N8C9=CC=CC=C9C[C@@]8([H])C(N7)S(O)(=O)=O)=CC(NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCCCC(=O)NCCN%10C(=O)CC(SC[C@H](N)C(O)=O)C%10=O)=C5)C(OC)=C4
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
