INER I-123 | norepinephrine reuptake inhibitor | CAS#918657-07-5

MedKoo Cat#: 124874 | Name: INER I-123

Description:

WARNING: This product is for research use only, not for human or veterinary use.

INER I-123 is a norepinephrine reuptake inhibitor.

Chemical Structure

INER I-123

CAS#918657-07-5

Theoretical Analysis

MedKoo Cat#: 124874

Name: INER I-123

CAS#: 918657-07-5

Chemical Formula: C17H18123INO2

Exact Mass: 391.0400

Molecular Weight: 391.24

Elemental Analysis: C, 52.19; H, 4.64; I, 31.41; N, 3.58; O, 8.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

UNII-8AAP8G8ODE; 8AAP8G8ODE; Iner I-123; (123I)INER; 123-I INER; 918657-07-5; (123)I-INER;

IUPAC/Chemical Name

(S)-2-((S)-(2-(iodo-123I)phenoxy)(phenyl)methyl)morpholine

InChi Key

BHMLFPOTZYRDKA-KAJUPPCBSA-N

InChi Code

InChI=1S/C17H18INO2/c18-14-8-4-5-9-15(14)21-17(13-6-2-1-3-7-13)16-12-19-10-11-20-16/h1-9,16-17,19H,10-12H2/t16-,17-/m0/s1/i18-4

SMILES Code

[H][C@]1(CNCCO1)[C@@H](OC2=CC=CC=C2[123I])C3=CC=CC=C3

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 391.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tavares AA, Barret O, Batis J, Alagille D, Koren A, Papin C, Kudej G, Nice K, Kordower JH, Cosgrove KP, Kloczynski T, Brenner E, Seibyl J, Tamagnan G. Kinetic modeling and occupancy measures of the norepinephrine transporters in baboons using single photon emission computed tomography with (123)I-INER. Synapse. 2013 Jan;67(1):30-41. doi: 10.1002/syn.21613. Epub 2012 Oct 31. PMID: 23042643. 2: Tavares AA, Jobson NK, Dewar D, Sutherland A, Pimlott SL, Batis J, Barret O, Seibyl J, Tamagnan G. Iodine-123 labeled reboxetine analogues for imaging of noradrenaline transporter in brain using single photon emission computed tomography. Synapse. 2012 Nov;66(11):923-30. doi: 10.1002/syn.21585. Epub 2012 Jul 30. PMID: 22807144.