Olafertinib maleate is an orally available third-generation and selective inhibitor of certain epidermal growth factor receptor (EGFR) activating mutations, including the resistance mutation T790M, with potential antineoplastic activity. Activating mutations in the tyrosine kinase domain of EGFR are found in approximately 20% of patients with
MedKoo Cat#: 124800
Name: Olafertinib maleate
CAS#: 1660963-66-5
Chemical Formula: C33H32F2N6O6
Exact Mass: 646.2400
Molecular Weight: 646.65
Elemental Analysis: C, 61.29; H, 4.99; F, 5.88; N, 13.00; O, 14.84
The following data is based on the product molecular weight 646.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
