MedKoo Cat#: 124757 | Name: Sulclamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulclamide is a sulfamoylbenzoic acid derivative with diuretic activity.

Chemical Structure

Sulclamide
Sulclamide
CAS#2455-92-7

Theoretical Analysis

MedKoo Cat#: 124757

Name: Sulclamide

CAS#: 2455-92-7

Chemical Formula: C7H7ClN2O3S

Exact Mass: 233.9900

Molecular Weight: 234.65

Elemental Analysis: C, 35.83; H, 3.01; Cl, 15.11; N, 11.94; O, 20.45; S, 13.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Sulclamide; 4-Chloro-3-sulfamoylbenzamide; 2455-92-7; Sulclamid; Sulclamida
IUPAC/Chemical Name
4-chloro-3-sulfamoylbenzamide
InChi Key
WRLKLPDTRUYBBV-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H7ClN2O3S/c8-5-2-1-4(7(9)11)3-6(5)14(10,12)13/h1-3H,(H2,9,11)(H2,10,12,13)
SMILES Code
O=C(N)C1=CC=C(Cl)C(S(=O)(N)=O)=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 234.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Reitz AB, Smith GR, Parker MH. The role of sulfamide derivatives in medicinal chemistry: a patent review (2006-2008). Expert Opin Ther Pat. 2009 Oct;19(10):1449-53. doi: 10.1517/13543770903185920. PMID: 19650745. 2: Tian H, Ye N, Luo M. Sulfamide: A Promising Deep-Ultraviolet Nonlinear Optical Crystal Assembled from Polar Covalent [SO2 (NH2 )2 ] Tetrahedra. Angew Chem Int Ed Engl. 2022 Apr 19;61(17):e202200395. doi: 10.1002/anie.202200395. Epub 2022 Mar 2. PMID: 35179290. 3: Villalba ML, Palestro P, Ceruso M, Gonzalez Funes JL, Talevi A, Bruno Blanch L, Supuran CT, Gavernet L. Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action. Bioorg Med Chem. 2016 Feb 15;24(4):894-901. doi: 10.1016/j.bmc.2016.01.012. Epub 2016 Jan 8. PMID: 26795114.