MedKoo Cat#: 124742 | Name: Tubulin inhibitor 35
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tubulin inhibitor 35 (compound 6b) is a dual inhibitor of topoisomerase I and tubulin polymerization.

Chemical Structure

Tubulin inhibitor 35
Tubulin inhibitor 35
CAS#2247047-77-2

Theoretical Analysis

MedKoo Cat#: 124742

Name: Tubulin inhibitor 35

CAS#: 2247047-77-2

Chemical Formula: C21H21N3O

Exact Mass: 331.1685

Molecular Weight: 331.42

Elemental Analysis: C, 76.11; H, 6.39; N, 12.68; O, 4.83

Price and Availability

Size Price Availability Quantity
100mg USD 750.00 2 Weeks
200mg USD 1,150.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,650.00 2 Weeks
2g USD 5,650.00 2 Weeks
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Related CAS #
No Data
Synonym
Tubulin inhibitor 35; Tubulin inhibitor-35; Tubulin inhibitor35
IUPAC/Chemical Name
14-propyl-8,13,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
InChi Key
JSGWJWGKFPBVTK-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H21N3O/c1-2-12-23-18-10-6-4-8-16(18)21(25)24-13-11-15-14-7-3-5-9-17(14)22-19(15)20(23)24/h3-10,20,22H,2,11-13H2,1H3
SMILES Code
O=C(N(CCC1=C2NC3=C1C=CC=C3)C2N4CCC)C5=C4C=CC=C5
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 331.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Deng J, Long L, Peng X, Jiang W, Peng Y, Zhang X, Zhao Y, Tian Y, Wang Z, Zhuo L. N(14)-substituted evodiamine derivatives as dual topoisomerase 1/tubulin-Inhibiting anti-gastrointestinal tumor agents. Eur J Med Chem. 2023 Jul 5;255:115366. doi: 10.1016/j.ejmech.2023.115366. Epub 2023 Apr 20. PMID: 37099835.