WES-1 | inhibitor of carbonic anhydrase IX | CAS#2748673-86-9

MedKoo Cat#: 124738 | Name: WES-1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

WES-1 (Compound 8g) is an inhibitor of carbonic anhydrase IX (Ki: 55.9 μM).

Chemical Structure

WES-1

CAS#2748673-86-9

Theoretical Analysis

MedKoo Cat#: 124738

Name: WES-1

CAS#: 2748673-86-9

Chemical Formula: C20H20N4O3S

Exact Mass: 396.1256

Molecular Weight: 396.47

Elemental Analysis: C, 60.59; H, 5.08; N, 14.13; O, 12.11; S, 8.09

Price and Availability

Size	Price	Availability
100mg	USD 950.00	2 Weeks
200mg	USD 1,650.00	2 Weeks
500mg	USD 3,650.00	2 Weeks
1g	USD 4,650.00	2 Weeks
2g	USD 7,650.00	2 Weeks

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Related CAS #

No Data

Synonym

WES-1; WES1; WES 1

IUPAC/Chemical Name

2-(3-(2-methyl-6-(p-tolyl)pyridin-3-yl)ureido)benzenesulfonamide

InChi Key

BHEXZFRNIHDPAK-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H20N4O3S/c1-13-7-9-15(10-8-13)17-12-11-16(14(2)22-17)23-20(25)24-18-5-3-4-6-19(18)28(21,26)27/h3-12H,1-2H3,(H2,21,26,27)(H2,23,24,25)

SMILES Code

O=C(NC1=C(S(=O)(N)=O)C=CC=C1)NC2=CC=C(C3=CC=C(C)C=C3)N=C2C

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 396.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Abdel-Megied AM, Eldehna WM, Abdelrahman MA, Elbarbry FA. Development and Validation of High-Throughput Bioanalytical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method for the Quantification of Newly Synthesized Antitumor Carbonic Anhydrase Inhibitors in Human Plasma. Molecules. 2020 Dec 6;25(23):5753. doi: 10.3390/molecules25235753. PMID: 33291270; PMCID: PMC7730089.