MedKoo Cat#: 124737 | Name: Anti-NASH agent 1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Anti-NASH agent 1 (compound 3d),a derivative of Elafibranor (HY-16737),is a potent agonist of PPAR-α/δ.

Chemical Structure

Anti-NASH agent 1
Anti-NASH agent 1
CAS#2409685-41-0

Theoretical Analysis

MedKoo Cat#: 124737

Name: Anti-NASH agent 1

CAS#: 2409685-41-0

Chemical Formula: C26H33NO4

Exact Mass: 423.2410

Molecular Weight: 423.55

Elemental Analysis: C, 73.73; H, 7.85; N, 3.31; O, 15.11

Price and Availability

Size Price Availability Quantity
100mg USD 950.00 2 Weeks
200mg USD 1,650.00 2 Weeks
500mg USD 3,650.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 7,650.00 2 Weeks
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Related CAS #
No Data
Synonym
Anti-NASH agent 1; Anti-NASH agent-1; Anti NASH agent 1; Anti-NASH-agent 1
IUPAC/Chemical Name
tert-butyl (E)-2-(2,6-dimethyl-4-(3-(4-(methylamino)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoate
InChi Key
JMNQFYWMYKSSSA-NTEUORMPSA-N
InChi Code
InChI=1S/C26H33NO4/c1-17-15-19(9-14-22(28)20-10-12-21(27-8)13-11-20)16-18(2)23(17)30-26(6,7)24(29)31-25(3,4)5/h9-16,27H,1-8H3/b14-9+
SMILES Code
CC(C)(OC1=C(C)C=C(/C=C/C(C2=CC=C(NC)C=C2)=O)C=C1C)C(OC(C)(C)C)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 423.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Xiang C, Chen X, Yao J, Yang N, Yu J, Qiu Q, Zhang S, Kong X, Zhao L, Fan ZC, Yu P, Teng YO. Design, synthesis and anti-NASH effect evaluation of novel GFT505 derivatives in vitro and in vivo. Eur J Med Chem. 2023 Sep 5;257:115510. doi: 10.1016/j.ejmech.2023.115510. Epub 2023 May 29. PMID: 37269672.