MedKoo Cat#: 124731 | Name: AD-186
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AD186 is a potent and selective S1R agonist

Chemical Structure

AD-186
AD-186
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 124731

Name: AD-186

CAS#: N/A

Chemical Formula: C22H28N2

Exact Mass: 320.2252

Molecular Weight: 320.48

Elemental Analysis: C, 82.45; H, 8.81; N, 8.74

Price and Availability

Size Price Availability Quantity
100mg USD 950.00 2 Weeks
200mg USD 1,650.00 2 Weeks
500mg USD 3,250.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 7,650.00 2 Weeks
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Related CAS #
No Data
Synonym
AD-186; AD186; AD 186
IUPAC/Chemical Name
7-benzyl-2-phenethyl-2,7-diazaspiro[3.5]nonane
InChi Key
PDEOLLCFLXAXIM-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H28N2/c1-3-7-20(8-4-1)11-14-24-18-22(19-24)12-15-23(16-13-22)17-21-9-5-2-6-10-21/h1-10H,11-19H2
SMILES Code
N1(CCC2=CC=CC=C2)CC3(CCN(CC4=CC=CC=C4)CC3)C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 320.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Dichiara M, Ambrosio FA, Barbaraci C, González-Cano R, Costa G, Parenti C, Marrazzo A, Pasquinucci L, Cobos EJ, Alcaro S, Amata E. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands. ACS Chem Neurosci. 2023 May 17;14(10):1845-1858. doi: 10.1021/acschemneuro.3c00074. Epub 2023 May 8. PMID: 37155827; PMCID: PMC10197133.